Container integrity is critical to product protection
Testing for container integrity is key to ensuring containers are leak-free and can protect the critical process solutions and final products they contain. This testing is even more important in aseptic processes. That’s because container integrity can not only affect product sterility, but also process yield, product stability and several other important attributes.
Poor container integrity causes product adulteration and loss, which ultimately leads to higher costs and process downtime.
Indirect and direct container integrity testing methods
Direct container integrity testing methods include pressure decay testing, burst testing, and helium leak testing. Other methods can include dye-penetrant testing, bacterial ingress testing, and container sterility testing. However, these methods are often not as precise, open to interpretation, and can be prone to operator error.
Why fluoropolymer bottles are ideal for container integrity
Fluoropolymer bottles, vials, and jars are the best containers for applications requiring absolute integrity because of their unmatched durability, strong seal integrity, and imperviousness to a very wide range of temperatures. What’s more – Purillex® containers from Savillex are designed with ferrule-style closure systems, which are unmatched in the life science industry.
In this technical note, we show you in-depth the three testing methods Savillex uses to test all our Purillex bottles for container and closure system integrity in critical applications.
Once you’ve had a read-through, explore our complete Purillex product range and learn why they’re the cleanest, safest and highest performing bottles ever produced.